PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25986850-0	2015	Ginsenosides Regulate PXR/NF-kappaB Signaling and Attenuate Dextran Sulfate Sodium-Induced Colitis.	Ginsenosides	0-12	nuclear factor kappa B subunit 1	Homo sapiens	26-35	
25986850-2	2015	Here we found that ginsenosides restore PXR/NF-kappaB signaling in inflamed conditions without disrupting PXR function in normal conditions.	Ginsenosides	19-31	nuclear factor kappa B subunit 1	Homo sapiens	44-53	
25986850-3	2015	The effects and mechanisms of ginsenosides in regulating PXR/NF-kappaB signals were determined both in vitro and in vivo.	Ginsenosides	30-42	nuclear factor kappa B subunit 1	Homo sapiens	61-70	
25986850-4	2015	Ginsenosides significantly inhibited NF-kappaB activation and restored the expression of PXR target genes in tumor necrosis factor-alpha-stimulated LS174T cells.	Ginsenosides	0-12	nuclear factor kappa B subunit 1	Homo sapiens	37-46	
25986850-5	2015	Despite not being PXR agonists, ginsenosides repressed NF-kappaB activation in a PXR-dependent manner.	Ginsenosides	32-44	nuclear factor kappa B subunit 1	Homo sapiens	55-64	
25986850-6	2015	Ginsenosides significantly increased the physical association between PXR and the NF-kappaB p65 subunit and thereby decreased the nuclear translocation of p65.	Ginsenosides	0-12	nuclear factor kappa B subunit 1	Homo sapiens	82-91	
25986850-8	2015	Consistently, ginsenosides significantly attenuated dextran sulfate sodium-induced experimental colitis, which was associated with restored PXR/NF-kappaB signaling.	Ginsenosides	14-26	nuclear factor kappa B subunit 1	Homo sapiens	144-153	
25986850-9	2015	This study indicates that ginsenosides may elicit anti-inflammatory effects via targeting PXR/NF-kappaB interaction without disrupting PXR function in healthy conditions.	Ginsenosides	26-38	nuclear factor kappa B subunit 1	Homo sapiens	94-103