PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25964201-7 2015 Interestingly, cross-resistance to imatinib and enzastaurin (selective inhibitors of c-Kit and PKC-beta, respectively), was observed and the use of YK-4-279 with enzastaurin in vitro led to marked drug synergy, suggesting a potential role for combination therapies in the future. Imatinib Mesylate 35-43 protein kinase C beta Homo sapiens 95-103