PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25929520-1 2015 It is generally accepted that Friedreich"s ataxia (FRDA) is caused by a deficiency in frataxin expression, a mitochondrial protein involved in iron homeostasis, which mainly affects the brain, dorsal root ganglia of the spinal cord, heart and in certain cases the pancreas. Iron 143-147 frataxin Homo sapiens 51-55 25929520-1 2015 It is generally accepted that Friedreich"s ataxia (FRDA) is caused by a deficiency in frataxin expression, a mitochondrial protein involved in iron homeostasis, which mainly affects the brain, dorsal root ganglia of the spinal cord, heart and in certain cases the pancreas. Iron 143-147 frataxin Homo sapiens 86-94 25929520-11 2015 In conclusion, our data show that FRDA cells present altered expression of genes related to cell cycle, oxidative stress and iron homeostasis which may be implicated in the increased apoptotic levels. Iron 125-129 frataxin Homo sapiens 34-38