PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25922640-8 2015 Additionally, these increases of CYP3A4, SOD, and GPX1 were significantly reduced, while p21 was significantly increased in LMB+EGCG-treated cells compared to LMB-treated cells. epigallocatechin gallate 128-132 H3 histone pseudogene 16 Homo sapiens 89-92 25922640-10 2015 Our study first shows that LMB produces ROS and is possibly metabolized by CYP3A4, GPX1, and SOD in A549 cells, and combination treatment of LMB and EGCG augments LMB-induced cytotoxicity through enhanced ROS production and the modulation of drug metabolism and p21/survivin pathways. epigallocatechin gallate 149-153 H3 histone pseudogene 16 Homo sapiens 262-265