PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25795461-2 2015 In the present study, we show that this ERalpha-mediated upregulation was significantly reduced by two ER antagonists (fulvestrant and raloxifene) but was not affected by a third ER antagonist, 4-hydroxytamoxifen (4-OHTAM), a major active tamoxifen (TAM) metabolite. Raloxifene Hydrochloride 135-145 estrogen receptor 1 Homo sapiens 40-47