PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25745356-14	2015	Administration of morphine alone resulted in significantly increased expression of PKCgamma and NR1 proteins in the spinal cord.	Morphine	18-26	protein kinase C, gamma	Rattus norvegicus	83-91	
25745356-15	2015	These increased levels of expression of PKCgamma and NR1 were significantly inhibited by co-administration of morphine with melatonin.	Morphine	110-118	protein kinase C, gamma	Rattus norvegicus	40-48	
25745356-16	2015	CONCLUSIONS: Our findings demonstrate that melatonin have potential to attenuate repetitive morphine-induced hyperalgesia and tolerance, possibly by inhibiting PKCgamma and NR1 activities in the spinal cord.	Morphine	92-100	protein kinase C, gamma	Rattus norvegicus	160-168