PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25681707-5 2015 CASPASE3 activity and BAX expression were significantly raised in all MEHP-treated groups; BCL2 expression was elevated in 25 mumol/l group, while inhibited in 50 and 100 mumol/l groups; BAX/BCL2 ratio was increased in a typical dose-effect relationship. mono-(2-ethylhexyl)phthalate 70-74 caspase 3 Rattus norvegicus 0-8 25681707-6 2015 In conclusion, this study showed that MEHP exposure induced cell viability decrease and apoptosis, associated with increase of CASPASE3 activity and BAX/BCL2 ratio. mono-(2-ethylhexyl)phthalate 38-42 caspase 3 Rattus norvegicus 127-135 25681707-7 2015 Moreover, CASPASE3 activity showed a reversed dose-dependent effect in MEHP-treated groups, indicating there might exist other CASPASE-independent pathway involved in MEHP-induced apoptosis. mono-(2-ethylhexyl)phthalate 71-75 caspase 3 Rattus norvegicus 10-18 25681707-7 2015 Moreover, CASPASE3 activity showed a reversed dose-dependent effect in MEHP-treated groups, indicating there might exist other CASPASE-independent pathway involved in MEHP-induced apoptosis. mono-(2-ethylhexyl)phthalate 167-171 caspase 3 Rattus norvegicus 10-18