PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25662675-0 2015 The variant organic cation transporter 2 (OCT2)-T201M contribute to changes in insulin resistance in patients with type 2 diabetes treated with metformin. Metformin 144-153 solute carrier family 22 member 2 Homo sapiens 12-40 25662675-0 2015 The variant organic cation transporter 2 (OCT2)-T201M contribute to changes in insulin resistance in patients with type 2 diabetes treated with metformin. Metformin 144-153 solute carrier family 22 member 2 Homo sapiens 42-46 25662675-2 2015 Organic cation transporter 2 (OCT2) is responsible for 80% metformin clearance. Metformin 59-68 solute carrier family 22 member 2 Homo sapiens 0-28 25662675-2 2015 Organic cation transporter 2 (OCT2) is responsible for 80% metformin clearance. Metformin 59-68 solute carrier family 22 member 2 Homo sapiens 30-34 25662675-4 2015 In this study, we examined the role of OCT2-T201M (602 C>T) variant in insulin resistance in patients with type 2 diabetes (T2D) who were treated with metformin. Metformin 154-163 solute carrier family 22 member 2 Homo sapiens 39-43 25662675-11 2015 CONCLUSIONS: Our findings suggest that the loss-of-function variant OCT2-T201M (rs145450955) contribute to changes in insulin resistance and beta cell activity in patients with T2D treated with metformin. Metformin 194-203 solute carrier family 22 member 2 Homo sapiens 68-72