PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25655087-7	2015	Further study revealed that ALA exerted its bone-protective effects by inhibiting reactive oxygen species (ROS) generation by down-regulating Nox4 gene expression and protein synthesis and attenuating the transcriptional activation of NF-kappaB.	Thioctic Acid	28-31	NADPH oxidase 4	Rattus norvegicus	142-146	
25655087-9	2015	Taken together, the present study indicated that ALA promoted osteoblastic formation in H(2)O(2) -treated MC3T3-E1 cells and prevented OVX-induced bone loss in rats by regulating Nox4/ROS/NF-kappaB and Wnt/Lrp5/beta-catenin signaling pathways, which provided possible mechanisms of bone-protective effects in regulating osteoblastic formation and preventing bone loss.	Thioctic Acid	49-52	NADPH oxidase 4	Rattus norvegicus	179-183