PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25622857-0 2015 Activation of the NF-kappaB pathway as a mechanism of alcohol enhanced progression and metastasis of human hepatocellular carcinoma. Alcohols 54-61 nuclear factor kappa B subunit 1 Homo sapiens 18-27 25622857-7 2015 Consistently, higher expression of VEGF, MCP-1 and NF-kappaB was observed in HCC tissues of alcohol-drinkers. Alcohols 92-99 nuclear factor kappa B subunit 1 Homo sapiens 51-60 25622857-8 2015 Alcohol induced the accumulation of intracellular reactive oxygen species (ROS) and the activation of NF-kappaB signaling in HepG2 cells. Alcohols 0-7 nuclear factor kappa B subunit 1 Homo sapiens 102-111 25622857-9 2015 Conversely, blockage of alcohol-mediated ROS accumulation and NF-kappaB signaling inhibited alcohol-induced expression of VEGF and MCP-1, the tumor growth, angiogenesis and metastasis. Alcohols 92-99 nuclear factor kappa B subunit 1 Homo sapiens 62-71