PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25583361-3	2015	We investigated GnRH interactions with the His(7.36(305)) residue of the GnRH receptor, using functional and computational analysis of modified GnRH receptors and peptides.	Histidine	43-46	gonadotropin releasing hormone 1	Homo sapiens	16-20	
25583361-3	2015	We investigated GnRH interactions with the His(7.36(305)) residue of the GnRH receptor, using functional and computational analysis of modified GnRH receptors and peptides.	Histidine	43-46	gonadotropin releasing hormone 1	Homo sapiens	73-77	
25583361-3	2015	We investigated GnRH interactions with the His(7.36(305)) residue of the GnRH receptor, using functional and computational analysis of modified GnRH receptors and peptides.	Histidine	43-46	gonadotropin releasing hormone 1	Homo sapiens	73-77	
25583361-4	2015	Non-polar His(7.36(305)) substitutions decreased receptor affinity for GnRH four- to forty-fold, whereas GnRH signaling potency was more decreased (~150-fold).	Histidine	10-13	gonadotropin releasing hormone 1	Homo sapiens	71-75	
25583361-5	2015	Uncharged polar His(7.36(305)) substitutions decreased GnRH potency, but not affinity.	Histidine	16-19	gonadotropin releasing hormone 1	Homo sapiens	55-59	
25583361-6	2015	[2-Nal(3)]-GnRH retained high affinity at receptors with non-polar His(7.36(305)) substitutions, supporting a role for His(7.36(305)) in recognizing Trp(3) of GnRH.	Histidine	67-70	gonadotropin releasing hormone 1	Homo sapiens	11-15	
25583361-6	2015	[2-Nal(3)]-GnRH retained high affinity at receptors with non-polar His(7.36(305)) substitutions, supporting a role for His(7.36(305)) in recognizing Trp(3) of GnRH.	Histidine	119-122	gonadotropin releasing hormone 1	Homo sapiens	11-15	
25583361-8	2015	Results suggest that His(7.36(305)) of the GnRH receptor forms two distinct interactions that determine binding to Trp(3) and couple agonist binding to the conserved transmembrane domain network that activates GPCRs.	Histidine	21-24	gonadotropin releasing hormone 1	Homo sapiens	43-47