PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25484141-0 2015 Targeting the Androgen Receptor Confers In Vivo Cross-resistance Between Enzalutamide and Docetaxel, But Not Cabazitaxel, in Castration-resistant Prostate Cancer. Docetaxel 90-99 androgen receptor Homo sapiens 14-31 25484141-2 2015 However, concerns regarding cross-resistance between the taxanes docetaxel and cabazitaxel and these AR-targeted agents have arisen, and the optimal drug treatment sequence is unknown. Docetaxel 65-74 androgen receptor Homo sapiens 101-103 25484141-6 2015 Docetaxel inhibited tumor growth, AR nuclear localization, and AR-regulated gene expression in enzalutamide-naive tumors, but did not in enzalutamide-resistant tumors, demonstrating in vivo cross-resistance. Docetaxel 0-9 androgen receptor Homo sapiens 34-36 25484141-6 2015 Docetaxel inhibited tumor growth, AR nuclear localization, and AR-regulated gene expression in enzalutamide-naive tumors, but did not in enzalutamide-resistant tumors, demonstrating in vivo cross-resistance. Docetaxel 0-9 androgen receptor Homo sapiens 63-65 25484141-8 2015 These findings demonstrate that the AR pathway is able to confer in vivo cross-resistance between enzalutamide and docetaxel, but not cabazitaxel, in CRPC. Docetaxel 115-124 androgen receptor Homo sapiens 36-38