PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2547112-7 1989 The reduction in the number of HeLa cells with abnormal metaphase configurations after exposure to 2-OHE2 plus quinalizarin (an inhibitor of catechol-O-methyltransferase) indicated that the production of 2-MeOE2 is necessary for the formation of abnormal spindles in metaphase. 2-hydroxyestradiol 99-105 catechol-O-methyltransferase Homo sapiens 141-169