PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25462231-1 2015 Diseases triggered by an abnormally high level of cortisol (hypercortisolism), such as the Cushing"s and metabolic syndromes, could be successfully tackled by inhibitors of CYP11B1, a steroidal cytochrome P450 enzyme that catalyzes the last hydroxylation step of the cortisol biosynthesis. Hydrocortisone 50-58 cytochrome P450 family 11 subfamily B member 1 Homo sapiens 173-180