PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25458910-0 2015 Randomized trial to evaluate azithromycin"s effects on serum and upper airway IL-8 levels and recurrent wheezing in infants with respiratory syncytial virus bronchiolitis. Azithromycin 29-41 C-X-C motif chemokine ligand 8 Homo sapiens 78-82 25458910-3 2015 OBJECTIVES: We sought to investigate whether azithromycin treatment during RSV bronchiolitis reduces serum and nasal lavage IL-8 levels and the occurrence of postbronchiolitis recurrent wheezing. Azithromycin 45-57 C-X-C motif chemokine ligand 8 Homo sapiens 124-128 25458910-7 2015 RESULTS: Compared with placebo, azithromycin treatment did not reduce serum IL-8 levels at day 8 (P = .6) but resulted in a greater decrease in nasal lavage fluid IL-8 levels by day 15 (P = .03). Azithromycin 32-44 C-X-C motif chemokine ligand 8 Homo sapiens 163-167 25458910-10 2015 CONCLUSION: In this proof-of-concept study azithromycin treatment during RSV bronchiolitis reduced upper airway IL-8 levels, prolonged the time to the third wheezing episode, and reduced overall respiratory morbidity over the subsequent year. Azithromycin 43-55 C-X-C motif chemokine ligand 8 Homo sapiens 112-116