PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25415199-2 2014 As2O3 induced this two cell lines apoptosis via activation of caspase-3/8 and cleavage of poly (ADP-ribose) polymerase (PARP), a DNA repair enzyme. Arsenic Trioxide 0-5 caspase 3 Homo sapiens 62-118 25415199-7 2014 Our findings suggest that As2O3 may induce apoptosis in MUTZ-1 and SKM-1 cells by two independent pathways: first, by activation of caspase-3/8 and PARP; and second, by inhibition of NF-kappaB activity, which results in downregulation of hTERT expression. Arsenic Trioxide 26-31 caspase 3 Homo sapiens 132-143