PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25383959-0 2014 Celastrol stimulates hypoxia-inducible factor-1 activity in tumor cells by initiating the ROS/Akt/p70S6K signaling pathway and enhancing hypoxia-inducible factor-1alpha protein synthesis. celastrol 0-9 ribosomal protein S6 kinase B1 Homo sapiens 98-104 25383959-5 2014 Instead, Celastrol induced the accumulation of the HIF-1alpha protein by inducing ROS and activating Akt/p70S6K signaling to promote HIF-1alpha translation. celastrol 9-18 ribosomal protein S6 kinase B1 Homo sapiens 105-111