PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25293882-6 2014 Niacin (vitamin B3) is able to control the excess tryptophan oxidation, correcting tryptophan depletion, and therefore represents an interesting strategy to improve CD4 recovery.We aim to design a crossover proof-of-concept study to assess supplementation with an extended-release form of niacin (Niaspan FCT ) in combination with antiretroviral therapy, compared to antiretroviral therapy alone, on T-cell immune activation as defined by changes in the percentage of CD8+ CD38+ HLA-DR+ T-cells. Niacin 0-6 CD38 molecule Homo sapiens 473-477