PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25278738-5 2013 Genes encoding the liver cytochrome P-450 (CYP) enzymes that are involved with the metabolism of methadone (CYP2B6, 3A4 and 2C19) were selected and genotyped in this cohort. Methadone 97-106 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 108-114 25278738-6 2013 We found that the SNPs on CYP2B6 were associated with plasma S-methadone concentration; SNPs on CYP3A4 were associated with withdrawal symptoms and side effects; and SNPs on CYP2C19 were associated with methadone dose. Methadone 63-72 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 26-32 25278738-6 2013 We found that the SNPs on CYP2B6 were associated with plasma S-methadone concentration; SNPs on CYP3A4 were associated with withdrawal symptoms and side effects; and SNPs on CYP2C19 were associated with methadone dose. Methadone 203-212 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 26-32