PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25272052-7 2015 P2X7R antagonists, such as the oxidized ATP, A438079, brilliant blue G, and broad spectrum P2 receptor antagonist suramin, attenuated Tat-induced CCL2 release in a calcium- and extracellular signal-regulated kinase (ERK)1/2-dependent manner. Calcium 164-171 C-C motif chemokine ligand 2 Homo sapiens 146-150 25272052-13 2015 We proposed the following cascade for Tat-mediated CCL2 release from astrocytes: Tat mediates increase in P2X7R expression, which on activation evokes increase in intracellular calcium, which further leads to phosphorylation of ERK1/2 followed by the release of CCL2 from astrocytes. Calcium 177-184 C-C motif chemokine ligand 2 Homo sapiens 51-55 25272052-13 2015 We proposed the following cascade for Tat-mediated CCL2 release from astrocytes: Tat mediates increase in P2X7R expression, which on activation evokes increase in intracellular calcium, which further leads to phosphorylation of ERK1/2 followed by the release of CCL2 from astrocytes. Calcium 177-184 C-C motif chemokine ligand 2 Homo sapiens 262-266