PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25263346-0	2014	PGE2 reduces MMP-14 and increases plasminogen activator inhibitor-1 in cardiac fibroblasts.	Dinoprostone	0-4	matrix metallopeptidase 14	Rattus norvegicus	13-19	
25263346-0	2014	PGE2 reduces MMP-14 and increases plasminogen activator inhibitor-1 in cardiac fibroblasts.	Dinoprostone	0-4	serpin family E member 1	Rattus norvegicus	34-67	
25263346-1	2014	Prostaglandin E2 (PGE2) is elevated during cardiac injury and we have previously shown that mice lacking the PGE2 EP4 receptor display dilated cardiomyopathy (DCM) with increased expression of the membrane type matrix metalloproteinase, MMP-14.	Dinoprostone	0-16	prostaglandin E receptor 4	Rattus norvegicus	114-117	
25263346-1	2014	Prostaglandin E2 (PGE2) is elevated during cardiac injury and we have previously shown that mice lacking the PGE2 EP4 receptor display dilated cardiomyopathy (DCM) with increased expression of the membrane type matrix metalloproteinase, MMP-14.	Dinoprostone	0-16	matrix metallopeptidase 14 (membrane-inserted)	Mus musculus	197-243	
25263346-1	2014	Prostaglandin E2 (PGE2) is elevated during cardiac injury and we have previously shown that mice lacking the PGE2 EP4 receptor display dilated cardiomyopathy (DCM) with increased expression of the membrane type matrix metalloproteinase, MMP-14.	Dinoprostone	18-22	prostaglandin E receptor 4	Rattus norvegicus	114-117	
25263346-1	2014	Prostaglandin E2 (PGE2) is elevated during cardiac injury and we have previously shown that mice lacking the PGE2 EP4 receptor display dilated cardiomyopathy (DCM) with increased expression of the membrane type matrix metalloproteinase, MMP-14.	Dinoprostone	18-22	matrix metallopeptidase 14 (membrane-inserted)	Mus musculus	197-243	
25263346-2	2014	We thus hypothesized that PGE2 regulates expression of MMP-14 and also affects fibroblast migration.	Dinoprostone	26-30	matrix metallopeptidase 14	Rattus norvegicus	55-61	
25263346-5	2014	PGE2 reduced expression of MMP-14 and these effects were antagonized by an EP4 antagonist.	Dinoprostone	0-4	matrix metallopeptidase 14	Rattus norvegicus	27-33	
25263346-5	2014	PGE2 reduced expression of MMP-14 and these effects were antagonized by an EP4 antagonist.	Dinoprostone	0-4	prostaglandin E receptor 4	Rattus norvegicus	75-78	
25263346-6	2014	An EP4 agonist mimicked the effect of PGE2.	Dinoprostone	38-42	prostaglandin E receptor 4	Rattus norvegicus	3-6	
25263346-7	2014	PGE2 also increased mRNA and protein levels of plasminogen activator inhibitor-1 (PAI-1), an inhibitor of MMP activation.	Dinoprostone	0-4	serpin family E member 1	Rattus norvegicus	47-80	
25263346-7	2014	PGE2 also increased mRNA and protein levels of plasminogen activator inhibitor-1 (PAI-1), an inhibitor of MMP activation.	Dinoprostone	0-4	serpin family E member 1	Rattus norvegicus	82-87	
25263346-8	2014	However, PGE2-stimulation of PAI-1 was mediated by the EP1/EP3 receptor and not EP4.	Dinoprostone	9-13	serpin family E member 1	Rattus norvegicus	29-34	
25263346-8	2014	However, PGE2-stimulation of PAI-1 was mediated by the EP1/EP3 receptor and not EP4.	Dinoprostone	9-13	prostaglandin E receptor 1	Rattus norvegicus	55-71