PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25258409-8 2014 Furthermore, nicotine inhibited the IL-6 production of CD4 T cells in the DSS-induced inflamed colonic mucosa. Nicotine 13-21 interleukin 6 Mus musculus 36-40 25258409-10 2014 Nicotine markedly inhibited the elevation of TNF-alpha and IL-6 mRNA as well as phosphorylated signal transducer and activator of transcription (Stat) 3 expression in the colons of the tumor model mice. Nicotine 0-8 interleukin 6 Mus musculus 59-63 25258409-12 2014 Furthermore, it is presumed that nicotine downregulates the expression of inflammatory mediators such as IL-6/Stat3 and TNF-alpha, thereby reducing the colonic tumorigenesis associated with chronic colitis. Nicotine 33-41 interleukin 6 Mus musculus 105-109