PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25183586-2	2014	Cobalt ions activate human toll-like receptor 4 (TLR4), which normally responds to bacterial lipopolysaccharide (LPS) in sepsis.	Cobalt	0-6	toll like receptor 4	Homo sapiens	27-47	
25183586-2	2014	Cobalt ions activate human toll-like receptor 4 (TLR4), which normally responds to bacterial lipopolysaccharide (LPS) in sepsis.	Cobalt	0-6	toll like receptor 4	Homo sapiens	49-53	
25183586-7	2014	Experiments were also performed in the presence of CLI-095, a TLR4-specific antagonist which abrogated the cobalt-mediated increase in IL-8 and CXCL10 expression.	Cobalt	107-113	toll like receptor 4	Homo sapiens	62-66	
25183586-8	2014	These findings suggest that cobalt ions induce inflammation similar to that observed during sepsis by the simultaneous activation of two TLR4-mediated signalling pathways.	Cobalt	28-34	toll like receptor 4	Homo sapiens	137-141