PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25170806-0	2014	Curcumin promotes KLF5 proteasome degradation through downregulating YAP/TAZ in bladder cancer cells.	Curcumin	0-8	Kruppel-like factor 5	Mus musculus	18-22	
25170806-0	2014	Curcumin promotes KLF5 proteasome degradation through downregulating YAP/TAZ in bladder cancer cells.	Curcumin	0-8	yes-associated protein 1	Mus musculus	69-72	
25170806-0	2014	Curcumin promotes KLF5 proteasome degradation through downregulating YAP/TAZ in bladder cancer cells.	Curcumin	0-8	tafazzin, phospholipid-lysophospholipid transacylase	Mus musculus	73-76	
25170806-2	2014	In this study, we demonstrated that curcumin targeted KLF5 by promoting its proteasome degradation, but not by inhibiting its transcription in bladder cancer cells.	Curcumin	36-44	Kruppel-like factor 5	Mus musculus	54-58	
25170806-3	2014	We also demonstrated that lentivirus-based knockdown of KLF5 inhibited cancer cell growth, while over-expression of a Flag-tagged KLF5 could partially reverse the effects of curcumin on cell growth and cyclin D1 expression.	Curcumin	174-182	Kruppel-like factor 5	Mus musculus	130-134	
25170806-3	2014	We also demonstrated that lentivirus-based knockdown of KLF5 inhibited cancer cell growth, while over-expression of a Flag-tagged KLF5 could partially reverse the effects of curcumin on cell growth and cyclin D1 expression.	Curcumin	174-182	cyclin D1	Mus musculus	202-211	
25170806-4	2014	Furthermore, we found that curcumin could down-regulate the expression of Hippo pathway effectors, YAP and TAZ, which have been reported to protect KLF5 protein from degradation.	Curcumin	27-35	yes-associated protein 1	Mus musculus	99-102	
25170806-4	2014	Furthermore, we found that curcumin could down-regulate the expression of Hippo pathway effectors, YAP and TAZ, which have been reported to protect KLF5 protein from degradation.	Curcumin	27-35	tafazzin, phospholipid-lysophospholipid transacylase	Mus musculus	107-110	
25170806-4	2014	Furthermore, we found that curcumin could down-regulate the expression of Hippo pathway effectors, YAP and TAZ, which have been reported to protect KLF5 protein from degradation.	Curcumin	27-35	Kruppel-like factor 5	Mus musculus	148-152	
25170806-7	2014	Thus, our data indicates that curcumin promotes KLF5 proteasome-dependent degradation through targeting YAP/TAZ in bladder cancer cells and also suggests the therapeutic potential of curcumin in the treatment of bladder cancer.	Curcumin	30-38	Kruppel-like factor 5	Mus musculus	48-52	
25170806-7	2014	Thus, our data indicates that curcumin promotes KLF5 proteasome-dependent degradation through targeting YAP/TAZ in bladder cancer cells and also suggests the therapeutic potential of curcumin in the treatment of bladder cancer.	Curcumin	30-38	yes-associated protein 1	Mus musculus	104-107	
25170806-7	2014	Thus, our data indicates that curcumin promotes KLF5 proteasome-dependent degradation through targeting YAP/TAZ in bladder cancer cells and also suggests the therapeutic potential of curcumin in the treatment of bladder cancer.	Curcumin	30-38	tafazzin, phospholipid-lysophospholipid transacylase	Mus musculus	108-111	
25170806-7	2014	Thus, our data indicates that curcumin promotes KLF5 proteasome-dependent degradation through targeting YAP/TAZ in bladder cancer cells and also suggests the therapeutic potential of curcumin in the treatment of bladder cancer.	Curcumin	183-191	Kruppel-like factor 5	Mus musculus	48-52