PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25113166-3 2014 By examining the interactions of estradiol (E2) and progesterone (P4) in women, we propose that changes in physiologic reproductive hormone templates of exposure and timing can affect fertility and even cancer through the silencing or amplification of gene products; such as P53 and Bcl-2 in women. Estradiol 33-42 tumor protein p53 Homo sapiens 275-278