PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25110320-3 2014 A net up-regulation of survival signaling, involving the extracellular signal-regulated kinase (ERK) and phosphoinositide 3-kinase (PI3K)/Akt phosphorylation pathways, was observed in U937 promonocytic cells cultivated over time in the presence of a low micromolar concentration of the oxysterol. Oxysterols 286-295 mitogen-activated protein kinase 1 Homo sapiens 57-94 25110320-5 2014 In turn, stimulation of ERK and PI3K/Akt both significantly quenched ROS steady state and markedly phosphorylated Bad, thereby determining a marked delay of the oxysterol s proapoptotic action. Oxysterols 161-170 mitogen-activated protein kinase 1 Homo sapiens 24-27