PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25082450-0	2014	Depigmentation caused by application of the active brightening material, rhododendrol, is related to tyrosinase activity at a certain threshold.	rhododendrol	73-85	tyrosinase	Homo sapiens	101-111	
25082450-2	2014	Unexpected depigmentation of the skin characterized with the diverse symptoms was reported in some subjects who used a tyrosinase-competitive inhibiting quasi-drug, rhododendrol.	rhododendrol	165-177	tyrosinase	Homo sapiens	119-129	
25082450-5	2014	The RNAi technology was utilized to confirm the effect of tyrosinase to induce the cytotoxicity of rhododendrol and liquid chromatography-tandem mass spectrometry was introduced to detect rhododendrol and its metabolites in the presence of tyrosinase.	rhododendrol	99-111	tyrosinase	Homo sapiens	58-68	
25082450-7	2014	Treatment with a tyrosinase-specific siRNA was shown to dramatically rescue the rhododendrol-induced melanocyte impairment.	rhododendrol	80-92	tyrosinase	Homo sapiens	17-27	
25082450-10	2014	CONCLUSION: The generation of a tyrosinase-catalyzed hydroxyl-metabolite is one of the causes for the diminishment of the melanocyte viability by rhododendrol.	rhododendrol	146-158	tyrosinase	Homo sapiens	32-42