PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25047145-9 2014 In addition to the loss of GAGs and tissue mechanical properties, IL-1alpha treatment induced the expression of matrix metalloproteinases and increased the production of the inflammatory mediators nitric oxide and prostaglandin E2 . Nitric Oxide 197-209 interleukin 1 alpha Mus musculus 66-75