PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25000369-0	2014	Preventive effects of siRNA targeting PPARgamma gene on steroid-induced osteonecrosis in rabbits.	Steroids	56-63	peroxisome proliferator-activated receptor gamma	Oryctolagus cuniculus	38-47	
25000369-1	2014	UNLABELLED: PURPOSES/AIM: Glucocorticoid steroids can induce expression of PPARgamma gene and enhance adipogenesis by bone marrow mesenchymal stem cells (BMSCs), which may result in osteonecrosis of the femoral head.	Steroids	41-49	peroxisome proliferator-activated receptor gamma	Oryctolagus cuniculus	75-84	
25000369-3	2014	We hypothesized that siRNA targeting PPARgamma gene may prevent steroid-induced adipogenesis and osteonecrosis in rabbit.	Steroids	64-71	peroxisome proliferator-activated receptor gamma	Oryctolagus cuniculus	37-46	
25000369-4	2014	The purpose of this study was to evaluate the preventive effects of siRNA targeting PPARgamma gene on steroid-induced adipogenesis and osteonecrosis.	Steroids	102-109	peroxisome proliferator-activated receptor gamma	Oryctolagus cuniculus	84-93	
25000369-7	2014	RESULTS: The levels of PPARgamma gene expression were decreased while the levels of osteocalcin and Runx2 gene expression were increased in rabbits treated with dexamethasone and recombinant adenovirus shuttle vector carrying siRNA targeting PPARgamma gene (Group S), compared to rabbits treated either with dexamethasone alone (Group M) or with both dexamethasone and a vector carrying irrelative sequence (Group Con).	Dexamethasone	161-174	peroxisome proliferator-activated receptor gamma	Oryctolagus cuniculus	23-32	
25000369-7	2014	RESULTS: The levels of PPARgamma gene expression were decreased while the levels of osteocalcin and Runx2 gene expression were increased in rabbits treated with dexamethasone and recombinant adenovirus shuttle vector carrying siRNA targeting PPARgamma gene (Group S), compared to rabbits treated either with dexamethasone alone (Group M) or with both dexamethasone and a vector carrying irrelative sequence (Group Con).	Dexamethasone	161-174	osteocalcin	Oryctolagus cuniculus	84-95	
25000369-7	2014	RESULTS: The levels of PPARgamma gene expression were decreased while the levels of osteocalcin and Runx2 gene expression were increased in rabbits treated with dexamethasone and recombinant adenovirus shuttle vector carrying siRNA targeting PPARgamma gene (Group S), compared to rabbits treated either with dexamethasone alone (Group M) or with both dexamethasone and a vector carrying irrelative sequence (Group Con).	Dexamethasone	161-174	runt-related transcription factor 2	Oryctolagus cuniculus	100-105	
25000369-7	2014	RESULTS: The levels of PPARgamma gene expression were decreased while the levels of osteocalcin and Runx2 gene expression were increased in rabbits treated with dexamethasone and recombinant adenovirus shuttle vector carrying siRNA targeting PPARgamma gene (Group S), compared to rabbits treated either with dexamethasone alone (Group M) or with both dexamethasone and a vector carrying irrelative sequence (Group Con).	Dexamethasone	161-174	peroxisome proliferator-activated receptor gamma	Oryctolagus cuniculus	242-251	
25000369-7	2014	RESULTS: The levels of PPARgamma gene expression were decreased while the levels of osteocalcin and Runx2 gene expression were increased in rabbits treated with dexamethasone and recombinant adenovirus shuttle vector carrying siRNA targeting PPARgamma gene (Group S), compared to rabbits treated either with dexamethasone alone (Group M) or with both dexamethasone and a vector carrying irrelative sequence (Group Con).	Dexamethasone	308-321	peroxisome proliferator-activated receptor gamma	Oryctolagus cuniculus	242-251	
25000369-7	2014	RESULTS: The levels of PPARgamma gene expression were decreased while the levels of osteocalcin and Runx2 gene expression were increased in rabbits treated with dexamethasone and recombinant adenovirus shuttle vector carrying siRNA targeting PPARgamma gene (Group S), compared to rabbits treated either with dexamethasone alone (Group M) or with both dexamethasone and a vector carrying irrelative sequence (Group Con).	Dexamethasone	308-321	peroxisome proliferator-activated receptor gamma	Oryctolagus cuniculus	242-251	
25000369-10	2014	CONCLUSION: siRNA targeting PPARgamma gene can inhibit adipogenic differentiation of BMSCs and prevent steroid-induced osteonecrosis in rabbit.	Steroids	103-110	peroxisome proliferator-activated receptor gamma	Oryctolagus cuniculus	28-37