PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24894716-4 2014 We demonstrated that 17beta-estradiol (E2) and the GPER-selective ligand G-1 triggered a GPER/EGFR/ERK/c-fos signaling pathway that leads to increased VEGF via upregulation of HIF1alpha. Estradiol 21-37 mitogen-activated protein kinase 1 Homo sapiens 99-102