PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24742583-0 2014 Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication. sulforaphane 0-12 gap junction protein alpha 1 Homo sapiens 84-88 24742583-7 2014 The bioactive substance sulforaphane enhanced Cx43 and E-cadherin levels, inhibited the CSC markers c-Met and CD133, improved the functional morphology of GJs and enhanced GJIC. sulforaphane 24-36 gap junction protein alpha 1 Homo sapiens 46-50 24742583-8 2014 Sulforaphane altered the phosphorylation of several kinases and their substrates and inhibition of GSK3, JNK and PKC prevented sulforaphane-induced CX43 expression. sulforaphane 127-139 gap junction protein alpha 1 Homo sapiens 148-152 24742583-9 2014 The sulforaphane-mediated expression of Cx43 was not correlated with enhanced Cx43 RNA expression, acetylated histone binding and Cx43 promoter de-methylation, suggesting that posttranslational phosphorylation is the dominant regulatory mechanism. sulforaphane 4-16 gap junction protein alpha 1 Homo sapiens 40-44