PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24685625-9	2014	Western blot and immunofluorescence analysis showed that exposure to celastrol increased HSP-70 and Bcl-2 expression but decreased NFkappaB activity, phosphorylated glycogen synthase kinase-3beta (GSK-3beta) at tyrosine 216 and cyclooxygenase-2 (COX-2) expression, Abeta accumulation together with a reduction of superoxide and hydrogen peroxide generation.	celastrol	69-78	heat shock protein family A (Hsp70) member 4	Homo sapiens	89-95	
24685625-10	2014	HSP-70 siRNA abolished celastrol mediated cytoprotection.	celastrol	23-32	heat shock protein family A (Hsp70) member 4	Homo sapiens	0-6	
24685625-11	2014	CONCLUSION: This study demonstrates that celastrol reduced both LPS-induced cell death and Abeta production in vitro through increasing HSP-70 and Bcl-2 expression and reducing NFkappaB, COX-2, and GSK-3beta expression and oxidative stress.	celastrol	41-50	heat shock protein family A (Hsp70) member 4	Homo sapiens	136-142