PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24671507-1 2014 PURPOSE: To investigate the efficacy and safety of combining vandetanib, an orally available multi-targeted tyrosine kinase inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2) and epidermal growth factor receptor (EGFR), with bicalutamide in patients with metastatic castration-resistant prostate cancer (mCRPC). vandetanib 61-71 epidermal growth factor receptor Homo sapiens 185-189