PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24644001-0 2014 Metformin sensitizes EGFR-TKI-resistant human lung cancer cells in vitro and in vivo through inhibition of IL-6 signaling and EMT reversal. Metformin 0-9 epidermal growth factor receptor Homo sapiens 21-25 24644001-4 2014 This study aims to investigate the effect of metformin on sensitizing EGFR-TKI-resistant human lung cancer cells in vitro and in vivo through inhibition of IL-6 signaling and EMT reversal. Metformin 45-54 epidermal growth factor receptor Homo sapiens 70-74 24644001-10 2014 CONCLUSION: Metformin, generally considered nontoxic and remarkably inexpensive, might be used in combination with TKIs in patients with non-small cell lung cancer, harboring EGFR mutations to overcome TKI resistance and prolong survival. Metformin 12-21 epidermal growth factor receptor Homo sapiens 175-179