PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24526685-0	2014	The inducible nitric-oxide synthase (iNOS)/Src axis mediates Toll-like receptor 3 tyrosine 759 phosphorylation and enhances its signal transduction, leading to interferon-beta synthesis in macrophages.	Tyrosine	82-90	toll like receptor 3	Homo sapiens	61-81	
24526685-1	2014	Double-stranded RNA (dsRNA) induces phosphorylation of Toll-like receptor 3 (TLR3) at tyrosine 759 and subsequently triggers signaling pathways to promote interferon-beta (IFN-beta) production.	Tyrosine	86-94	toll like receptor 3	Homo sapiens	55-75	
24526685-1	2014	Double-stranded RNA (dsRNA) induces phosphorylation of Toll-like receptor 3 (TLR3) at tyrosine 759 and subsequently triggers signaling pathways to promote interferon-beta (IFN-beta) production.	Tyrosine	86-94	toll like receptor 3	Homo sapiens	77-81	
24526685-2	2014	In this study, we found that dsRNA stimulation induces biphasic TLR3 Tyr-759 phosphorylation in macrophages.	Tyrosine	69-72	toll like receptor 3	Homo sapiens	64-68	
24526685-4	2014	Interestingly, Src phosphorylated TLR3 Tyr-759 in vitro and in vivo.	Tyrosine	39-42	toll like receptor 3	Homo sapiens	34-38	
24526685-5	2014	However, knockdown of Src abolished the late phase of TLR3 Tyr-759 phosphorylation and decreased the nuclear accumulation of interferon regulatory factors 3 and 7 (IRF3 and -7) and IFN-beta production.	Tyrosine	59-62	toll like receptor 3	Homo sapiens	54-58	
24526685-7	2014	Notably, via down-regulation of Src, dsRNA-elicited TLR3 Tyr-759 phosphorylation, the nuclear accumulation of IRF3/IRF7, and IFN-beta generation were inhibited in inducible nitric-oxide synthase (iNOS)-null macrophages.	Tyrosine	57-60	toll like receptor 3	Homo sapiens	52-56