PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2451866-0	1988	In vivo metabolism of CCl4 by rats pretreated with chlordecone, mirex, or phenobarbital.	Chlordecone	51-62	C-C motif chemokine ligand 4	Rattus norvegicus	22-26	
2451866-1	1988	The propensity of chlordecone (CD) to potentiate hepatotoxic and lethal effects of CCl4 is well established.	Chlordecone	18-29	C-C motif chemokine ligand 4	Rattus norvegicus	83-87	
2451866-1	1988	The propensity of chlordecone (CD) to potentiate hepatotoxic and lethal effects of CCl4 is well established.	Chlordecone	31-33	C-C motif chemokine ligand 4	Rattus norvegicus	83-87	
2451866-3	1988	The purpose of this study was to test the possibility that CD potentiates the toxicity of CCl4 by increasing the metabolism of CCl4 to a greater degree than either PB or M. We compared the in vivo metabolism of CCl4 in rats pretreated with CD, M, or PB, by measuring the hepatic content of 14CCl4, the expiration of 14CCl4, expiration of 14CCl4-derived 14CO2, and lipid peroxidation.	Chlordecone	59-61	C-C motif chemokine ligand 4	Rattus norvegicus	90-94	
2451866-3	1988	The purpose of this study was to test the possibility that CD potentiates the toxicity of CCl4 by increasing the metabolism of CCl4 to a greater degree than either PB or M. We compared the in vivo metabolism of CCl4 in rats pretreated with CD, M, or PB, by measuring the hepatic content of 14CCl4, the expiration of 14CCl4, expiration of 14CCl4-derived 14CO2, and lipid peroxidation.	Chlordecone	59-61	C-C motif chemokine ligand 4	Rattus norvegicus	127-131	
2451866-3	1988	The purpose of this study was to test the possibility that CD potentiates the toxicity of CCl4 by increasing the metabolism of CCl4 to a greater degree than either PB or M. We compared the in vivo metabolism of CCl4 in rats pretreated with CD, M, or PB, by measuring the hepatic content of 14CCl4, the expiration of 14CCl4, expiration of 14CCl4-derived 14CO2, and lipid peroxidation.	Chlordecone	59-61	C-C motif chemokine ligand 4	Rattus norvegicus	127-131	
2451866-8	1988	Expiration of 14CO2 measured during the 6 hr after CCl4 administration was increased in animals pretreated with PB or CD.	Chlordecone	118-120	C-C motif chemokine ligand 4	Rattus norvegicus	51-55	
2451866-11	1988	These data indicate that a single oral administration of CD (10 mg/kg) 24 hr prior to CCl4 administration (100 microliter/kg) enhances the oxidative metabolism of CCl4 but to a lesser extent than PB (80 mg/kg, ip, twice), which is in inverse relationship to the potentiation of the hepatotoxic and lethal effects of CCl4 associated with these pretreatments.	Chlordecone	57-59	C-C motif chemokine ligand 4	Rattus norvegicus	163-167	
2451866-11	1988	These data indicate that a single oral administration of CD (10 mg/kg) 24 hr prior to CCl4 administration (100 microliter/kg) enhances the oxidative metabolism of CCl4 but to a lesser extent than PB (80 mg/kg, ip, twice), which is in inverse relationship to the potentiation of the hepatotoxic and lethal effects of CCl4 associated with these pretreatments.	Chlordecone	57-59	C-C motif chemokine ligand 4	Rattus norvegicus	163-167