PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24495916-3 2014 We reported previously that cardiac-specific deletion of N-methyl-d-aspartate receptor-1 (NMDAR1) ameliorates homocysteine-posed cardiac threats, and in this study, we aim to explore the role of NMDAR1 in epigenetic mechanisms of heart failure, using cardiomyocytes during hyperhomocysteinemia (HHcy). Homocysteine 110-122 glutamate receptor, ionotropic, NMDA1 (zeta 1) Mus musculus 57-88 24495916-3 2014 We reported previously that cardiac-specific deletion of N-methyl-d-aspartate receptor-1 (NMDAR1) ameliorates homocysteine-posed cardiac threats, and in this study, we aim to explore the role of NMDAR1 in epigenetic mechanisms of heart failure, using cardiomyocytes during hyperhomocysteinemia (HHcy). nmdar1 90-96 glutamate receptor, ionotropic, NMDA1 (zeta 1) Mus musculus 57-88 24495916-4 2014 High homocysteine levels activate NMDAR1, which consequently leads to abnormal DNA methylation vs. histone acetylation through modulation of DNA methyltransferase 1 (DNMT1), HDAC1, miRNAs, and MMP9 in cardiomyocytes. Homocysteine 5-17 DNA methyltransferase (cytosine-5) 1 Mus musculus 141-164 24495916-4 2014 High homocysteine levels activate NMDAR1, which consequently leads to abnormal DNA methylation vs. histone acetylation through modulation of DNA methyltransferase 1 (DNMT1), HDAC1, miRNAs, and MMP9 in cardiomyocytes. Homocysteine 5-17 DNA methyltransferase (cytosine-5) 1 Mus musculus 166-171 24495916-4 2014 High homocysteine levels activate NMDAR1, which consequently leads to abnormal DNA methylation vs. histone acetylation through modulation of DNA methyltransferase 1 (DNMT1), HDAC1, miRNAs, and MMP9 in cardiomyocytes. Homocysteine 5-17 histone deacetylase 1 Mus musculus 174-179 24495916-4 2014 High homocysteine levels activate NMDAR1, which consequently leads to abnormal DNA methylation vs. histone acetylation through modulation of DNA methyltransferase 1 (DNMT1), HDAC1, miRNAs, and MMP9 in cardiomyocytes. Homocysteine 5-17 matrix metallopeptidase 9 Mus musculus 193-197 24495916-12 2014 High homocysteine levels instigate cardiovascular remodeling through NMDAR1, miR-133a, miR-499, and DNMT1. Homocysteine 5-17 microRNA 615 Mus musculus 77-80 24495916-12 2014 High homocysteine levels instigate cardiovascular remodeling through NMDAR1, miR-133a, miR-499, and DNMT1. Homocysteine 5-17 microRNA 499 Mus musculus 87-94 24495916-12 2014 High homocysteine levels instigate cardiovascular remodeling through NMDAR1, miR-133a, miR-499, and DNMT1. Homocysteine 5-17 DNA methyltransferase (cytosine-5) 1 Mus musculus 100-105 24495916-12 2014 High homocysteine levels instigate cardiovascular remodeling through NMDAR1, miR-133a, miR-499, and DNMT1. 133a 81-85 microRNA 615 Mus musculus 77-80