PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24462458-0	2014	Dicoumarol sensitizes renal cell carcinoma Caki cells to TRAIL-induced apoptosis through down-regulation of Bcl-2, Mcl-1 and c-FLIP in a NQO1-independent manner.	Dicumarol	0-10	CASP8 and FADD like apoptosis regulator	Homo sapiens	125-131	
24462458-4	2014	We found that dicoumarol transcriptionally down-regulated Bcl-2 expression via inhibition of NF-kappaB and CREB activity, whereas it down-regulated Mcl-1 and c-FLIP expression at the post-translational level.	Dicumarol	14-24	CASP8 and FADD like apoptosis regulator	Homo sapiens	158-164	
24462458-5	2014	Overexpression of Bcl-2, Mcl-1, or c-FLIP overcame the dicoumarol plus TRAIL-induced apoptosis, indicating that down-regualtion of these anti-apoptotic proteins may critically contribute to the sensitizing effect of dicoumarol on TRAIL-mediated apoptosis.	Dicumarol	55-65	CASP8 and FADD like apoptosis regulator	Homo sapiens	35-41	
24462458-5	2014	Overexpression of Bcl-2, Mcl-1, or c-FLIP overcame the dicoumarol plus TRAIL-induced apoptosis, indicating that down-regualtion of these anti-apoptotic proteins may critically contribute to the sensitizing effect of dicoumarol on TRAIL-mediated apoptosis.	Dicumarol	216-226	CASP8 and FADD like apoptosis regulator	Homo sapiens	35-41