PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24456472-1 2014 We recently reported the discovery of AM-8553 (1), a potent and selective piperidinone inhibitor of the MDM2-p53 interaction. 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(2-hydroxypentan-3-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid 38-45 MDM2 proto-oncogene Homo sapiens 104-108