PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24403860-7	2013	Activation of AMPK by metformin triggered a growth inhibitory signal but also increased BCA2 protein levels, which correlated with AKT activation and could be curbed by an AMPK inhibitor, suggesting a potential feedback mechanism from pAMPKalpha1 to pAkt to BCA2.	Metformin	22-31	AKT serine/threonine kinase 1	Homo sapiens	131-134	
24403860-8	2013	Finally, BCA2 siRNA, or inhibition of its upstream stabilizing kinase AKT, increased the growth inhibitory effect of metformin in multiple breast cancer cell lines, supporting the conclusion that BCA2 weakens metformin"s efficacy.	Metformin	117-126	AKT serine/threonine kinase 1	Homo sapiens	70-73	
24403860-8	2013	Finally, BCA2 siRNA, or inhibition of its upstream stabilizing kinase AKT, increased the growth inhibitory effect of metformin in multiple breast cancer cell lines, supporting the conclusion that BCA2 weakens metformin"s efficacy.	Metformin	209-218	AKT serine/threonine kinase 1	Homo sapiens	70-73