PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24399074-0 2014 Vandetanib-induced inhibition of neuroblastoma cell migration and invasion is associated with downregulation of the SDF-1/CXCR4 axis and matrix metalloproteinase 14. vandetanib 0-10 C-X-C motif chemokine receptor 4 Homo sapiens 122-127 24399074-8 2014 In addition, our data showed that the levels of C-X-C chemokine receptor type 4 (CXCR4) and matrix metalloproteinase 14 (MMP14) mRNA expression in NB cell lines treated with vandetanib were significantly lower than those in the cells that were treated with vehicle (p<0.01) and similar results were obtained for protein levels as determined by western blotting and immunofluorescence analysis. vandetanib 174-184 C-X-C motif chemokine receptor 4 Homo sapiens 48-79 24399074-8 2014 In addition, our data showed that the levels of C-X-C chemokine receptor type 4 (CXCR4) and matrix metalloproteinase 14 (MMP14) mRNA expression in NB cell lines treated with vandetanib were significantly lower than those in the cells that were treated with vehicle (p<0.01) and similar results were obtained for protein levels as determined by western blotting and immunofluorescence analysis. vandetanib 174-184 C-X-C motif chemokine receptor 4 Homo sapiens 81-86 24399074-10 2014 The potential mechanisms for the inhibition of NB migration and invasion by vandetanib may partly be attributed to the ability of vandetanib to suppress the expression of CXCR4 and MMP14 in human NB cells. vandetanib 76-86 C-X-C motif chemokine receptor 4 Homo sapiens 171-176 24399074-10 2014 The potential mechanisms for the inhibition of NB migration and invasion by vandetanib may partly be attributed to the ability of vandetanib to suppress the expression of CXCR4 and MMP14 in human NB cells. vandetanib 130-140 C-X-C motif chemokine receptor 4 Homo sapiens 171-176