PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24376706-3 2013 Four of the compounds inhibited efflux of two ABCB1 substrates, Hoechst 33342 and daunorubicin, in MDCKII-ABCB1 cells: Olomoucine II most strongly, followed by roscovitine, purvalanol A, and flavopiridol. alvocidib 191-203 ATP binding cassette subfamily B member 1 Homo sapiens 46-51 24376706-5 2013 In addition, purvalanol A, SNS-032 and flavopiridol lowered the stimulated ATPase activity in ABCB1 membrane preparations, while olomoucine II and roscovitine not only inhibited the stimulated ATPase but also significantly activated the basal ABCB1 ATPase, suggesting that these two CDKi are ABCB1 substrates. alvocidib 39-51 ATP binding cassette subfamily B member 1 Homo sapiens 94-99 24376706-5 2013 In addition, purvalanol A, SNS-032 and flavopiridol lowered the stimulated ATPase activity in ABCB1 membrane preparations, while olomoucine II and roscovitine not only inhibited the stimulated ATPase but also significantly activated the basal ABCB1 ATPase, suggesting that these two CDKi are ABCB1 substrates. alvocidib 39-51 ATP binding cassette subfamily B member 1 Homo sapiens 243-248 24376706-5 2013 In addition, purvalanol A, SNS-032 and flavopiridol lowered the stimulated ATPase activity in ABCB1 membrane preparations, while olomoucine II and roscovitine not only inhibited the stimulated ATPase but also significantly activated the basal ABCB1 ATPase, suggesting that these two CDKi are ABCB1 substrates. alvocidib 39-51 ATP binding cassette subfamily B member 1 Homo sapiens 243-248