PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24331695-11 2013 Moreover, sorafenib alone significantly inhibited the RAF/MEK/ERK and STAT3 pathways, with the fold-changes of p-C-RAF, p-ERK1/2 and p-STAT3 being 0.56 +/- 0.05, 0.54 +/- 0.02 and 0.36 +/- 0.02, respectively (all P less than 0.01); 5-FU alone produced no significant effects on these pathways. Sorafenib 10-19 zinc fingers and homeoboxes 2 Homo sapiens 54-57 24331695-11 2013 Moreover, sorafenib alone significantly inhibited the RAF/MEK/ERK and STAT3 pathways, with the fold-changes of p-C-RAF, p-ERK1/2 and p-STAT3 being 0.56 +/- 0.05, 0.54 +/- 0.02 and 0.36 +/- 0.02, respectively (all P less than 0.01); 5-FU alone produced no significant effects on these pathways. Sorafenib 10-19 zinc fingers and homeoboxes 2 Homo sapiens 115-118 24331695-14 2013 Sorafenib-inhibited RAF/MEK/ERK and STAT3 signaling and cyclinD1 expression may have induced the observed G1phase arrest and S phase reduction, thereby reducing the cells" sensitivity to 5-FU. Sorafenib 0-9 zinc fingers and homeoboxes 2 Homo sapiens 20-23