PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24302004-7 2014 Activation of AMPK by metformin inhibited mTORC1-STAT3 signaling, thereby preventing excess amino acid-impaired insulin signaling. Metformin 22-31 CREB regulated transcription coactivator 1 Mus musculus 42-48 24302004-9 2014 Chronic administration of either metformin or rapamycin inhibited the HPD-activated mTORC1/STAT3/Notch1 signaling pathway and prevented hepatic insulin resistance. Metformin 33-42 CREB regulated transcription coactivator 1 Mus musculus 84-90