PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24200972-5 2014 Lapatinib-resistant cells have an increased Src kinase activity and persistent levels of activation of ERK1/2 and AKT compared with parental cells. Lapatinib 0-9 AKT serine/threonine kinase 1 Homo sapiens 114-117 24200972-6 2014 Treatment with the Src inhibitor saracatinib in combination with lapatinib reduces AKT and ERK1/2 phosphorylation and restores the sensitivity of resistant cells to lapatinib. Lapatinib 65-74 AKT serine/threonine kinase 1 Homo sapiens 83-86