PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24200969-7 2014 Further analysis of 46 melanoma cell lines that harbored BRAF mutation showed that 7 pathways, including TNFalpha, EGFR, IFNalpha, hypoxia, IFNgamma, STAT3, and MYC, were significantly differently expressed in AZD6244-resistant compared with responsive melanoma cells. AZD 6244 210-217 B-Raf proto-oncogene, serine/threonine kinase Homo sapiens 57-61 24200969-8 2014 A SVM classifier built on this 7-pathway activation pattern correctly predicted the response of 10 BRAF-mutated melanoma cell lines to the MEK inhibitor AZD6244 in our experiments. AZD 6244 153-160 B-Raf proto-oncogene, serine/threonine kinase Homo sapiens 99-103