PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2419314-1 1985 AY-9944 (trans-1,4-bis(2-chlorobenzylaminoethyl)cyclohexane dihydrochloride), a cationic amphiphilic drug, caused a rapid, irreversible and dose-dependent reduction of acid sphingomyelinase activity in normal human fibroblasts without changing the activities of other lysosomal hydrolases tested. trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride 0-7 sphingomyelin phosphodiesterase 1 Homo sapiens 168-189 2419314-1 1985 AY-9944 (trans-1,4-bis(2-chlorobenzylaminoethyl)cyclohexane dihydrochloride), a cationic amphiphilic drug, caused a rapid, irreversible and dose-dependent reduction of acid sphingomyelinase activity in normal human fibroblasts without changing the activities of other lysosomal hydrolases tested. trans-1,4-bis(2-chlorobenzylaminoethyl)cyclohexane dihydrochloride 9-75 sphingomyelin phosphodiesterase 1 Homo sapiens 168-189