PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24160919-2 2013 In the formation of the male hormone dehydroepiandrosterone, pregnenolone is first hydroxylated by P450 CYP17A1 at the 17-carbon, followed a second round of catalysis by the same enzyme that cleaves the C17-C20 bond, releasing acetic acid and the 17-keto product. Dehydroepiandrosterone 37-59 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 104-111