PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24098639-0 2013 New potential therapeutic approach for the treatment of B-Cell malignancies using chlorambucil/hydroxychloroquine-loaded anti-CD20 nanoparticles. Chlorambucil 82-94 keratin 20 Homo sapiens 126-130 24098639-3 2013 In this contribution, we propose a novel therapeutic approach in which relatively high doses of Hydroxychloroquine and Chlorambucil were loaded into biodegradable nanoparticles coated with an anti-CD20 antibody. Chlorambucil 119-131 keratin 20 Homo sapiens 197-201 24098639-8 2013 In vitro and in vivo data showed the ability of anti-CD20 nanoparticles loaded with Hydroxychloroquine and Chlorambucil to increase tumor cell killing in comparison to free cytotoxic agents or Rituximab. Chlorambucil 107-119 keratin 20 Homo sapiens 53-57 24098639-9 2013 These results shed light on the potential of anti-CD20 nanoparticles carrying Hydroxychloroquine and Chlorambucil for controlling a disseminated model of aggressive lymphoma, and lend credence to the idea of adopting this therapeutic approach for the treatment of B-cell disorders. Chlorambucil 101-113 keratin 20 Homo sapiens 50-54