PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24079644-6	2014	In these cells, caspase-3 was inhibited by ceramide-induced Akt phosphorylation, and by the induction of autophagic microtubule-associated protein-1 light-chain 3 lipidation.	Ceramides	43-51	AKT serine/threonine kinase 1	Homo sapiens	60-63	
24079644-9	2014	In cells from smokers, the prominent up-regulation of Akt pathways inhibited ceramide-triggered apoptosis, and was associated with elevated sphingosine and high-mobility group box 1, skewing the cell"s response toward autophagy and survival.	Ceramides	77-85	AKT serine/threonine kinase 1	Homo sapiens	54-57	
24079644-10	2014	In conclusion, the cell responses to ceramide are modulated by an intricate cross-talk between Akt signaling and sphingolipid metabolites, and profoundly modified by previous cigarette smoke exposure, which selects for an apoptosis-resistant phenotype.	Ceramides	37-45	AKT serine/threonine kinase 1	Homo sapiens	95-98